Effective parameters for stimulation of dissociated cultures using multi-electrode arrays
نویسندگان
چکیده
منابع مشابه
Effective parameters for stimulation of dissociated cultures using multi-electrode arrays.
Electrical stimulation through multi-electrode arrays is used to evoke activity in dissociated cultures of cortical neurons. We study the efficacies of a variety of pulse shapes under voltage control as well as current control, and determine useful parameter ranges that optimize efficacy while preventing damage through electrochemistry. For any pulse shape, stimulation is found to be mediated b...
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There is increasing interest in interfacing dissociated neuronal cultures with planar multielectrode arrays (MEAs) for the study of the dynamics of neuronal networks. Here we report on the successful use of three-dimensional tip electrode arrays (3D MEAs), originally developed for use with brain slices, for recording and stimulation of cultured neurons. We observed that many neurons grew direct...
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The recording of electrophysiological activities of brain neurons in the last half-century has been considered as one of the effective tools for the development of neuroscience. One of the techniques for recording the activity of nerve cells is the multi-electrode arrays (MEAs). Microelectrode arrays (MEAs) are usually employed to record electrical signals from electrogenic cells like neurons o...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2004
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2004.03.005